Molecule Details
| InChIKey | XFLXHBRVXWEPCZ-KRWDZBQOSA-N |
|---|---|
| Compound Name | (2S)-1-(2,4-dihydroxybenzoyl)-N,2-dimethyl-N-(quinoxalin-6-ylmethyl)-3,4-dihydro-2H-quinoline-6-carboxamide |
| Canonical SMILES | C[C@H]1CCc2cc(C(=O)N(C)Cc3ccc4nccnc4c3)ccc2N1C(=O)c1ccc(O)cc1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.2 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15118 | PDK1 | Homo sapiens | Human | PF10436 PF02518 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q15119 | PDK2 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q15120 | PDK3 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q16654 | PDK4 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |