Molecule Details
| InChIKey | XFLQIRAKKLNXRQ-UUWRZZSWSA-N |
|---|---|
| Canonical SMILES | CCCCC1(CCCC)CN(c2ccccc2)c2cc(SC)c(OCC(=O)N[C@@H](C(=O)NCC(=O)O)c3ccccc3)cc2S(=O)(=O)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.92 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB12486 |
|---|---|
| Drug Name | Elobixibat |
| CAS Number | 439087-18-0 |
| Groups | investigational |
| ATC Codes | A06AX09 |
| Description | Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. |
Categories: Alimentary Tract and Metabolism Amino Acids, Peptides, and Proteins Azepines Drugs for Constipation Oligopeptides Peptides Sulfur Compounds Thiepins
Cross-references: BindingDB: 77088 CHEMBL3039515 ChemSpider: 8115513 PubChem:9939892 PubChem:347828724 Wikipedia: Elobixibat
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q12908 | SLC10A2 | Ileal sodium/bile acid cotransporter | modulator | targets |