Molecule Details
InChIKeyXEOVWJYINDYNSM-UHFFFAOYSA-N
Compound NameSB 203580, Sulfone
Canonical SMILESCS(=O)(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.04
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
P48730 CSNK1D Homo sapiens Human PF00069 7.4 Ki ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
P49674 CSNK1E Homo sapiens Human PF00069 7.0 Kd ChEMBL
P09917 ALOX5 Homo sapiens Human PF00305 PF01477 6.7 IC50 ChEMBL;BindingDB
P48729 CSNK1A1 Homo sapiens Human PF00069 6.2 Ki ChEMBL