(S)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxoprop-1-enyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile

InChIKey	`XEAWPTQREKCGSA-UKTKYZJWSA-N`
Compound Name	(S)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxoprop-1-enyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile
Canonical SMILES	`Cc1c(Nc2c(C#N)cnc3sc(/C=C/C(=O)N4CC[C@H](N(C)C)C4)cc23)ccc2[nH]ccc12`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.57
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q04759	PRKCQ	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.8	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.5	pIC50	TTD_MultiTarget
Q05655	PRKCD	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.5	IC50	ChEMBL;BindingDB