4-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]oxazol-5-yl]-N-(1-phenylethyl)pyrimidin-2-amine

InChIKey	`XBAIEEJJCJHBDL-UHFFFAOYSA-N`
Compound Name	4-[6-(4-fluorophenyl)imidazo[2,1-b][1,3]oxazol-5-yl]-N-(1-phenylethyl)pyrimidin-2-amine
Canonical SMILES	`CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3occn23)n1)c1ccccc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	17
Pfam Stratification	Cross-Family
Avg pChEMBL	6.59
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P48730	CSNK1D	Homo sapiens	Human	PF00069	8.2	Ki	ChEMBL
P45984	MAPK9	Homo sapiens	Human	PF00069	7.3	Ki	ChEMBL
Q9Y6M4	CSNK1G3	Homo sapiens	Human	PF12605 PF00069	7.1	Ki	ChEMBL
O94806	PRKD3	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.8	Ki	ChEMBL
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.7	Ki	ChEMBL
P45983	MAPK8	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
Q7L7X3	TAOK1	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.5	Ki	ChEMBL
P78368	CSNK1G2	Homo sapiens	Human	PF12605 PF00069	6.5	Ki	ChEMBL
P42685	FRK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.4	Ki	ChEMBL
P48729	CSNK1A1	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q8N4C8	MINK1	Homo sapiens	Human	PF00780 PF00069	6.3	Ki	ChEMBL
Q9BZL6	PRKD2	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.3	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.2	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q9HCP0	CSNK1G1	Homo sapiens	Human	PF12605 PF00069	6.1	Ki	ChEMBL
Q9Y4K4	MAP4K5	Homo sapiens	Human	PF00780 PF00069	6.0	Ki	ChEMBL