Molecule Details
| InChIKey | XASOHFCUIQARJT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 8-Methoxy-6-{7-[2-(morpholin-4-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one |
| Canonical SMILES | COc1cc(-c2cnc3cc(OCCN4CCOCC4)ccn23)cc2c1C(=O)N(CC(F)(F)F)CC2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.11 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9Y2K2 | SIK3 | Homo sapiens | Human | PF00069 PF23312 | 7.6 | IC50 | ChEMBL |
| Q9H0K1 | SIK2 | Homo sapiens | Human | PF00069 PF23312 | 7.3 | IC50 | ChEMBL |
| O43353 | RIPK2 | Homo sapiens | Human | PF00619 PF07714 | 7.1 | IC50 | ChEMBL |
| P57059 | SIK1 | Homo sapiens | Human | PF00069 PF23312 | 6.4 | IC50 | ChEMBL |