Molecule Details
| InChIKey | XAEPFDVBAVYYLP-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-Butyl-4-(6,7-diethoxy-2,3-bis-hydroxymethyl-naphthalen-1-yl)-3,6-dihydro-1H-pyridin-2-one |
| Canonical SMILES | CCCCN1CC=C(c2c(CO)c(CO)cc3cc(OCC)c(OCC)cc23)CC1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.52 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.5 | IC50 | ChEMBL |