Molecule Details
| InChIKey | WZSVRUCBLPTNFX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-amino-3-naphthalen-1-yl-N-[5-(2-pyridin-4-ylethenyl)-3-pyridinyl]propanamide |
| Canonical SMILES | NC(Cc1cccc2ccccc12)C(=O)Nc1cncc(C=Cc2ccncc2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.0 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.6 | Ki | ChEMBL |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.0 | Ki | ChEMBL |
| P17612 | PRKACA | Homo sapiens | Human | PF00069 | 6.7 | Ki | ChEMBL |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.7 | Ki | ChEMBL |