Molecule Details
InChIKeyWZRFLSDVFPIXOV-LRQRDZAKSA-N
Compound NameGdc-0152
Canonical SMILESCN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1snnc1-c1ccccc1)C1CCCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.62
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12380
Drug NameGDC-0152
CAS Number873652-48-3
Groups investigational
ATC Codes nan
DescriptionGDC-0152 has been used in trials studying the treatment of Solid Cancers.

Categories: Cycloparaffins
Cross-references: BindingDB: 50388975 CHEMBL2063869 ChemSpider: 28521870 PubChem:46940575 PubChem:347828628 ZINC: ZINC000084654490
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96CA5 BIRC7 Homo sapiens Human PF00653 PF13920 7.8 Kd ChEMBL;BindingDB
Q9UH92 MLX Homo sapiens Human PF00010 7.8 Ki ChEMBL;BindingDB
Q13490 BIRC2 Homo sapiens Human PF00653 PF00619 PF21290 PF13920 7.8 IC50 ChEMBL;BindingDB
Q13489 BIRC3 Homo sapiens Human PF00653 PF00619 PF21290 PF13920 7.4 IC50 ChEMBL;BindingDB
P98170 XIAP Homo sapiens Human PF00653 PF21290 PF13920 7.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P98170 XIAP E3 ubiquitin-protein ligase XIAP modulator targets