2-[[4-(1H-indazol-6-ylamino)-1,3,5-triazin-2-yl]amino]benzoic acid

InChIKey	`WZISGNDZZPSYRP-UHFFFAOYSA-N`
Compound Name	2-[[4-(1H-indazol-6-ylamino)-1,3,5-triazin-2-yl]amino]benzoic acid
Canonical SMILES	`O=C(O)c1ccccc1Nc1ncnc(Nc2ccc3cn[nH]c3c2)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	6.62
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	7.8	Ki	ChEMBL
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	7.7	Ki	ChEMBL
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	7.2	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL
Q14680	MELK	Homo sapiens	Human	PF02149 PF00069 PF21594	6.8	Ki	ChEMBL
Q9H2X6	HIPK2	Homo sapiens	Human	PF00069	6.8	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P50750	CDK9	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
Q15078	CDK5R1	Homo sapiens	Human	PF03261	6.6	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q12851	MAP4K2	Homo sapiens	Human	PF00780 PF00069	6.5	Ki	ChEMBL
O94806	PRKD3	Homo sapiens	Human	PF00130 PF00169 PF00069 PF25525	6.4	Ki	ChEMBL
P43405	SYK	Homo sapiens	Human	PF07714 PF00017	6.3	Ki	ChEMBL
Q13188	STK3	Homo sapiens	Human	PF11629 PF00069	6.3	Ki	ChEMBL
O96013	PAK4	Homo sapiens	Human	PF00786 PF00069	6.0	Ki	ChEMBL
P11309	PIM1	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
P51817	PRKX	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
P52333	JAK3	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.0	Ki	ChEMBL