Molecule Details
InChIKeyWZBMMJKAHHOXRG-UHFFFAOYSA-N
Compound Name4-(2,4-Difluorophenyl)thieno[2,3-c]pyridine-2-carboxamide
Canonical SMILESNC(=O)c1cc2c(-c3ccc(F)cc3F)cncc2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.4
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P49840 GSK3A Homo sapiens Human PF00069 7.7 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.7 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.5 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.3 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.0 Ki ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 6.0 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.0 Ki ChEMBL