N-hydroxy-2-[5-(2-methylsulfanylpyrimidin-4-yl)thiophen-2-yl]sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide

InChIKey	`WYWULSIANADMTA-UHFFFAOYSA-N`
Compound Name	N-hydroxy-2-[5-(2-methylsulfanylpyrimidin-4-yl)thiophen-2-yl]sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide
Canonical SMILES	`CSc1nccc(-c2ccc(S(=O)(=O)N3Cc4ccccc4CC3C(=O)NO)s2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	7.7
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	7.7	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	7.7	pIC50	TTD_MultiTarget