InChIKey	WYWIFABBXFUGLM-UHFFFAOYSA-N
Compound Name	Oxymetazoline
Canonical SMILES	Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	17
Pfam Stratification	Cross-Family
Avg pChEMBL	7.23
Source	BindingDB;ChEMBL

DrugBank ID	DB00935
Drug Name	Oxymetazoline
CAS Number	1491-59-4
Groups	approved investigational
ATC Codes	S01GA04 D11AX27 R01AB07 R01AA05
Description	Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors.[A215542] Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of...

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Categories: Adrenergic Agents Adrenergic Agonists Adrenergic alpha-1 Receptor Agonists Adrenergic alpha-2 Receptor Agonists Adrenergic alpha-Agonists Agents producing tachycardia Agents that produce hypertension Autonomic Agents Cardiovascular Agents Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 Substrates Decongestants and Antiallergics Dermatologicals Imidazoles Increased Sympathetic Activity Nasal Decongestants Nasal Preparations Neurotransmitter Agents Ophthalmologicals Peripheral Nervous System Agents Respiratory System Agents Sensory Organs Sympathomimetics Sympathomimetics Used as Decongestants Sympathomimetics, Plain UGT1A9 Substrates Vasoconstriction Vasoconstrictor Agents

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Cross-references: BindingDB: 30712 ChEBI: 7862 CHEMBL762 ChemSpider: 4475 Drugs Product Database (DPD): 10195 Guide to Pharmacology: 124 IUPHAR: 124 C07363 D08322 PDB: J5C PharmGKB: PA164748840 PubChem:4636 PubChem:46505622 RxCUI: 7812 Therapeutic Targets Database: DAP000235 Wikipedia: Oxymetazoline ZINC: ZINC000000057435