Molecule Details
| InChIKey | WYUKVGVZYSCCDJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[4-(2-chloro-5-methylpyrimidin-4-yl)phenyl]-2,4-dihydroxy-N-[[4-[(3-methoxypyrrolidin-1-yl)methyl]phenyl]methyl]benzamide |
| Canonical SMILES | COC1CCN(Cc2ccc(CN(C(=O)c3ccc(O)cc3O)c3ccc(-c4nc(Cl)ncc4C)cc3)cc2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.88 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15119 | PDK2 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q15120 | PDK3 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q16654 | PDK4 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q15118 | PDK1 | Homo sapiens | Human | PF10436 PF02518 | 6.5 | IC50 | ChEMBL |