Molecule Details
InChIKeyWYLVFMBGPRCDQF-UHFFFAOYSA-N
Compound Name1-(1H-indol-3-yl)-3-[[5-(2-pyridin-4-ylethenyl)-3-pyridinyl]oxy]propan-2-ol
Canonical SMILESOC(COc1cncc(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Homologous
Avg pChEMBL6.34
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.1 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.1 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL