3-(3-aminophenyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

InChIKey	`WXPDCELKHNMODS-UHFFFAOYSA-N`
Compound Name	3-(3-aminophenyl)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILES	`Nc1cccc(-c2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.3
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.3	IC50	ChEMBL;BindingDB
P06493	CDK1	Homo sapiens	Human	PF00069	8.3	pIC50	TTD_MultiTarget
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	8.3	pIC50	TTD_MultiTarget