2-[[4-[(2,4-Diaminofuro[2,3-d]pyrimidin-5-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid

InChIKey	`WXINNGCGSCFUCR-UHFFFAOYSA-N`
Compound Name	2-[[4-[(2,4-Diaminofuro[2,3-d]pyrimidin-5-yl)methyl-methyl-amino]benzoyl]amino]pentanedioic acid
Canonical SMILES	`CN(Cc1coc2nc(N)nc(N)c12)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.93
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00374	DHFR	Homo sapiens	Human	PF00186	6.7	IC50	ChEMBL
P16184		Pneumocystis carinii	Pathogen	PF00186	7.5	IC50	ChEMBL
P00381	folA	Lacticaseibacillus casei	Pathogen	PF00186	6.7	IC50	ChEMBL