Molecule Details
InChIKeyWWGLOQFMJUZFTJ-UHFFFAOYSA-N
Compound NameHdac-IN-50
Canonical SMILESCOc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(CCCCCCC(=O)NO)c4)nc3c2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL8.88
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 9.7 IC50 ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 9.3 IC50 ChEMBL
P21802 FGFR2 Homo sapiens Human PF07679 PF13927 PF07714 8.9 IC50 ChEMBL
Q13547 HDAC1 Homo sapiens Human PF00850 8.9 IC50 ChEMBL
P22455 FGFR4 Homo sapiens Human PF07679 PF13927 PF07714 8.8 IC50 ChEMBL
Q92769 HDAC2 Homo sapiens Human PF00850 8.8 IC50 ChEMBL
Q9UBN7 HDAC6 Homo sapiens Human PF00850 PF02148 8.6 IC50 ChEMBL
Q9BY41 HDAC8 Homo sapiens Human PF00850 7.9 IC50 ChEMBL