Molecule Details
| InChIKey | WVTKBKWTSCPRNU-KYJUHHDHSA-N |
|---|---|
| Compound Name | Tetrandrine |
| Canonical SMILES | COc1ccc2cc1Oc1ccc(cc1)C[C@H]1c3cc(c(OC)cc3CCN1C)Oc1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.42 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14066 |
|---|---|
| Drug Name | Tetrandrine |
| CAS Number | 518-34-3 |
| Groups | investigational |
| ATC Codes | nan |
| Description | nan |
Categories: Agents causing hyperkalemia Alkaloids Anti-Infective Agents Antiarrhythmic agents Antimalarials Antineoplastic Agents Antineoplastic Agents, Phytogenic Antiparasitic Agents Antiprotozoals Bradycardia-Causing Agents Calcium Channel Blockers Calcium-Regulating Hormones and Agents Cardiovascular Agents Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Drugs, Chinese Herbal Heterocyclic Compounds, Fused-Ring Immunologic Factors Immunosuppressive Agents Isoquinolines Membrane Transport Modulators P-glycoprotein inhibitors Plant Extracts
Cross-references: ChEBI: 49 CHEMBL176045 ChemSpider: 65868 C09654 Wikipedia: Tetrandrine ZINC: ZINC000028116057