Molecule Details
InChIKeyWVSBGSNVCDAMCF-UHFFFAOYSA-N
Compound NameGsk-650394
Canonical SMILESO=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1C1CCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Homologous
Avg pChEMBL7.61
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96RR4 CAMKK2 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
O00141 SGK1 Homo sapiens Human PF00069 PF00433 7.9 IC50 ChEMBL;BindingDB
Q8N5S9 CAMKK1 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
O14965 AURKA Homo sapiens Human PF00069 6.5 Kd ChEMBL