Molecule Details
| InChIKey | WVNQJOXFTBTXOE-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-Hydroxy-3-[2-(4-phenoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acid |
| Canonical SMILES | O=C(O)c1cc2c(C#Cc3ccc(Oc4ccccc4)cc3)c(-c3ccccc3)oc2cc1O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.14 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q06124 | PTPN11 | Homo sapiens | Human | PF00017 PF00102 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q9Y2R2 | PTPN22 | Homo sapiens | Human | PF00102 | 6.2 | IC50 | ChEMBL;BindingDB |
| P29350 | PTPN6 | Homo sapiens | Human | PF00017 PF00102 | 6.1 | IC50 | ChEMBL;BindingDB |
| P51452 | DUSP3 | Homo sapiens | Human | PF00782 | 6.1 | IC50 | ChEMBL;BindingDB |
| P08575 | PTPRC | Homo sapiens | Human | PF12567 PF00041 PF12453 PF00102 | 6.0 | IC50 | ChEMBL;BindingDB |
| P9WIA1 | ptpA | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pathogen | PF01451 | 6.2 | IC50 | ChEMBL |