Molecule Details
InChIKeyWVMANZPBOBRWCB-UHFFFAOYSA-N
Compound Name7-butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine
Canonical SMILESCCCCc1c(-c2ccc(OC)cc2)[nH]c2nccnc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 9.3 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 9.3 Ki ChEMBL
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.2 IC50 ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.0 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.0 IC50 ChEMBL;BindingDB
Q14289 PTK2B Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.0 Ki ChEMBL;BindingDB