InChIKey	WVLOADHCBXTIJK-YNHQPCIGSA-N
Compound Name	Hydromorphone
Canonical SMILES	CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.51
Source	ChEMBL;BindingDB

DrugBank ID	DB00327
Drug Name	Hydromorphone
CAS Number	466-99-9
Groups	approved illicit investigational
ATC Codes	N02AA53 N02AA03 N02AG04
Description	Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine] that has been available clinically since 1920. Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a doubl...

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Categories: Alkaloids Analgesics Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Heterocyclic Compounds, Fused-Ring High-risk opioids Morphinans Morphine Derivatives Narcotics Natural Opium Alkaloids Nervous System Opiate Agonists Opiate Alkaloids Opioid Agonist Opioids Peripheral Nervous System Agents Phenanthrenes Semi-synthetic Opioids Sensory System Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome UGT1A3 substrates UGT2B7 substrates

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Cross-references: BindingDB: 50241341 ChEBI: 5790 CHEMBL398707 ChemSpider: 4447624 Drugs Product Database (DPD): 20280 C07042 PharmGKB: PA449918 PubChem:5284570 PubChem:46508700 RxCUI: 3423 Therapeutic Targets Database: DAP000472 Wikipedia: Hydromorphone ZINC: ZINC000000402954