4-(2-((2-Chloro-4-fluorophenyl)amino)-5-methyl-4-pyrimidinyl)-N-((1S)-1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide

InChIKey	`WUTVMXLIGHTZJC-OAQYLSRUSA-N`
Compound Name	4-(2-((2-Chloro-4-fluorophenyl)amino)-5-methyl-4-pyrimidinyl)-N-((1S)-1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide
Canonical SMILES	`Cc1cnc(Nc2ccc(F)cc2Cl)nc1-c1c[nH]c(C(=O)N[C@H](CO)c2cccc(Cl)c2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.26
Source	BindingDB;ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49840	GSK3A	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.4	Ki	BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL;BindingDB
Q02161	RHD	Homo sapiens	Human	PF00909	6.2	pIC50	TTD_MultiTarget
P24941	CDK2	Homo sapiens	Human	PF00069	6.1	pIC50	TTD_MultiTarget