Molecule Details
| InChIKey | WUECXCBONAGRSA-UHFFFAOYSA-N |
|---|---|
| Compound Name | Lixazinone |
| Canonical SMILES | CN(C(=O)CCCOc1ccc2c(c1)CN1CC(=O)NC1=N2)C1CCCCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.15 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19521 |
|---|---|
| Drug Name | Lixazinone |
| CAS Number | 94192-59-3 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Lixazinone is a small molecule drug. Lixazinone has a monoisotopic molecular weight of 384.22 Da. |
Categories: Heterocyclic Compounds, Fused-Ring
Cross-references: BindingDB: 50000871 CHEMBL69139
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 8.2 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 8.2 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 8.2 | IC50 | ChEMBL |
| Q13370 | PDE3B | Homo sapiens | Human | PF00233 | 8.0 | IC50 | ChEMBL |
| Q14432 | PDE3A | Homo sapiens | Human | PF00233 | 8.0 | IC50 | ChEMBL;BindingDB |