Molecule Details
InChIKeyWUDBUIUHVNECTM-UHFFFAOYSA-N
Compound Name4-(3-cyclohexyl-5-(4-fluoro-phenyl)-3H-imidazol-4-yl)pyrimidin-2-ylamine
Canonical SMILESNc1nccc(-c2c(-c3ccc(F)cc3)ncn2C2CCCCC2)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.3
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P48730 CSNK1D Homo sapiens Human PF00069 7.8 IC50 ChEMBL;BindingDB
P49674 CSNK1E Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.8 IC50 ChEMBL;BindingDB
Q16539 MAPK14 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB