Molecule Details
InChIKeyWUBHCQHBUVGGRX-UHFFFAOYSA-N
Compound Name5-(7-(4-Morpholinobutoxy)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)picolinonitrile
Canonical SMILESN#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCCN4CCOCC4)cc2-3)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.67
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 9.1 IC50 ChEMBL;BindingDB
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 7.1 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.9 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.6 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.5 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.4 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.3 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.2 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL