Molecule Details
InChIKeyWTKYHVUVQSLNBW-UHFFFAOYSA-N
Compound Name4-(4-thieno[2,3-d]pyrimidinylamino)-N-(4-((4-morpholinyl)methyl)phenyl)-1H-3-pyrazolecarboxamide
Canonical SMILESO=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1ncnc2sccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL8.6
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P36888 FLT3 Homo sapiens Human PF00047 PF07714 9.2 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 8.6 IC50 ChEMBL;BindingDB
P24941 CDK2 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 8.5 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.4 IC50 ChEMBL;BindingDB
Q00534 CDK6 Homo sapiens Human PF00069 8.4 IC50 ChEMBL