5-(4-((1-(tert-butyl)-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)-2-(((3R,4S)-1-(2-cyanoacetyl)-3-fluoropiperidin-4-yl)oxy)benzonitrile

InChIKey	`WTDOVWBIRCFQNH-CTNGQTDRSA-N`
Compound Name	5-(4-((1-(tert-butyl)-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)-2-(((3R,4S)-1-(2-cyanoacetyl)-3-fluoropiperidin-4-yl)oxy)benzonitrile
Canonical SMILES	`CC(C)(C)n1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CC#N)C[C@H]4F)c(C#N)c3)n2)cn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.53
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UHD2	TBK1	Homo sapiens	Human	PF00069 PF18394 PF18396	8.0	IC50	ChEMBL;BindingDB
Q14164	IKBKE	Homo sapiens	Human	PF00069 PF18394 PF18396	7.7	IC50	BindingDB
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	7.0	IC50	ChEMBL;BindingDB