InChIKey	WSEQXVZVJXJVFP-UHFFFAOYSA-N
Compound Name	Citalopram
Canonical SMILES	CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	7.04
Source	BindingDB;ChEMBL;TTD_MultiTarget

DrugBank ID	DB00215
Drug Name	Citalopram
CAS Number	59729-33-8
Groups	approved investigational
ATC Codes	N06AB04
Description	Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRI...

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Categories: Amines Antidepressive Agents Antidepressive Agents Indicated for Depression Antidepressive Agents, Second-Generation Benzofurans Central Nervous System Agents Central Nervous System Depressants Combined Inhibitors of Serotonin/Norepinephrine Reuptake Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (weak) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (weak) Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (weak) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring Highest Risk QTc-Prolonging Agents Hypoglycemia-Associated Agents Monoamine Oxidase A Substrates Nervous System Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Nitriles P-glycoprotein inhibitors P-glycoprotein substrates Propylamines Psychoanaleptics Psychotropic Drugs QTc Prolonging Agents Selective Serotonin Reuptake Inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT2 Receptor Antagonists Serotonin Agents Serotonin Modulators Serotonin Receptor Antagonists Vasodilating Agents

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Cross-references: BindingDB: 25870 ChEBI: 77397 CHEMBL549 ChemSpider: 2669 Drugs Product Database (DPD): 11847 C07572 D07704 PharmGKB: PA449015 PubChem:2771 PubChem:46508746 RxCUI: 2556 Therapeutic Targets Database: DAP000118 Wikipedia: Citalopram