InChIKey	WSEQXVZVJXJVFP-FQEVSTJZSA-N
Compound Name	Escitalopram
Canonical SMILES	CN(C)CCC[C@@]1(c2ccc(F)cc2)OCc2cc(C#N)ccc21
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.41
Source	ChEMBL;BindingDB

DrugBank ID	DB01175
Drug Name	Escitalopram
CAS Number	128196-01-0
Groups	approved investigational
ATC Codes	N06AB10
Description	Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram].[A185420] It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-e...

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Categories: Amines Anticholinergic Agents Antidepressive Agents Antidepressive Agents Indicated for Depression Antidepressive Agents, Second-Generation Benzofurans Central Nervous System Agents Central Nervous System Depressants Combined Inhibitors of Serotonin/Norepinephrine Reuptake Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (weak) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Heterocyclic Compounds, Fused-Ring Highest Risk QTc-Prolonging Agents Hypoglycemia-Associated Agents Membrane Transport Modulators Monoamine Oxidase A Substrates Muscarinic Antagonists Nervous System Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Nitriles P-glycoprotein substrates Photosensitizing Agents Propylamines Psychoanaleptics Psychotropic Drugs QTc Prolonging Agents Selective Serotonin Reuptake Inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin Agents Serotonin Modulators

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Cross-references: BindingDB: 50302225 ChEBI: 36791 CHEMBL1508 ChemSpider: 129277 Drugs Product Database (DPD): 13585 PDB: 68P PharmGKB: PA10074 PubChem:146570 PubChem:46507040 RxCUI: 321988 Therapeutic Targets Database: DAP000741 Wikipedia: Escitalopram ZINC: ZINC000003800706