Molecule Details
InChIKeyWRZNQKSBJJKEBD-UHFFFAOYSA-N
Compound Name1-(7-Ethylquinolin-4-yl)-3-[6-(trifluoromethyl)-2-pyridinyl]urea
Canonical SMILESCCc1ccc2c(NC(=O)Nc3cccc(C(F)(F)F)n3)ccnc2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.98
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 7.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 6.9 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.6 Ki ChEMBL
Q04912 MST1R Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.4 Ki ChEMBL