Molecule Details
| InChIKey | WRUUGTRCQOWXEG-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | NCCC(O)(P(=O)(O)O)P(=O)(O)O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.71 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB00282 |
|---|---|
| Drug Name | Pamidronic acid |
| CAS Number | 40391-99-9 |
| Groups | approved investigational |
| ATC Codes | M05BA03 |
| Description | Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977.[A203267] The second generation bisphosphonates are less common as third generation bisphosphonates, s... |
Categories: Agents Causing Muscle Toxicity Antineoplastic Agents Bisphosphonates Bone Density Conservation Agents Drugs Affecting Bone Structure and Mineralization Drugs for Treatment of Bone Diseases Musculo-Skeletal System Nephrotoxic agents Organophosphonates Organophosphorus Compounds
Cross-references: BindingDB: 12581 ChEBI: 7903 CHEMBL834 ChemSpider: 4512 Drugs Product Database (DPD): 896 C07395 D07281 PDB: 210 PharmGKB: PA450767 PubChem:4674 PubChem:46504823 RxCUI: 11473 Therapeutic Targets Database: DAP001416 Wikipedia: Pamidronic_acid ZINC: ZINC000003812862