Molecule Details
InChIKeyWQIJXHGCGUZFIC-JMRMXLIVSA-N
Canonical SMILESC#Cc1c(F)ccc2cc(O)cc(-c3cc4c5c(nc(OC[C@@]67CCCN6C[C@H](F)C7)nc5c3F)N3C[C@H]5CC[C@H](N5)[C@H]3CO4)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL9.28
SourceBindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 9.3 IC50 BindingDB
P01116 KRAS Homo sapiens Human PF00071 9.2 IC50 BindingDB