Molecule Details
InChIKeyWQFGNANQTYLQBP-UHFFFAOYSA-N
Compound NameN-[4-(difluoromethylsulfanyl)phenyl]-2-(4-pyridin-3-ylphenyl)acetamide
Canonical SMILESO=C(Cc1ccc(-c2cccnc2)cc1)Nc1ccc(SC(F)F)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.48
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.2 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.7 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.7 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 6.7 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 6.6 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.5 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.3 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.2 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.1 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
Q14164 IKBKE Homo sapiens Human PF00069 PF18394 PF18396 6.0 Ki ChEMBL