Molecule Details
| InChIKey | WPYGCZCMGMVGNO-UHFFFAOYSA-N |
|---|---|
| Compound Name | Fluperamide |
| Canonical SMILES | CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1)(c1ccccc1)c1ccccc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.4 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB20128 |
|---|---|
| Drug Name | Fluperamide |
| CAS Number | 53179-10-5 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Fluperamide is a small molecule drug. Fluperamide has a monoisotopic molecular weight of 544.21 Da. |
Cross-references: BindingDB: 50017686 CHEMBL421665 ZINC: ZINC000004216287
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P35372 | OPRM1 | Homo sapiens | Human | PF00001 | 10.0 | Ki | ChEMBL;BindingDB |
| P35498 | SCN1A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q99250 | SCN2A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 6.5 | IC50 | ChEMBL |
| Q9NY46 | SCN3A | Homo sapiens | Human | PF00520 PF24609 PF06512 PF11933 | 6.5 | IC50 | ChEMBL |