Molecule Details
InChIKeyWPHNAFYBBIAYKY-UHFFFAOYSA-N
Compound Name5-(5-chloro-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-(4-chlorophenyl)-1-cyclopropyl-3-(trifluoromethyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one
Canonical SMILESCn1cc(N2C(=O)c3c(c(C(F)(F)F)nn3C3CC3)C2c2ccc(Cl)cc2)cc(Cl)c1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.67
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P25440 BRD2 Homo sapiens Human PF17035 PF00439 6.8 IC50 ChEMBL;BindingDB
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 6.7 IC50 ChEMBL;BindingDB
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 6.5 IC50 ChEMBL;BindingDB