Target not found.
Molecule Details
InChIKeyWOTLXQZLXOXMFD-UHFFFAOYSA-N
Compound Name5-(6-Ethynyl-7-methoxy-1,4-dihydroindeno[2,1-d]pyrazol-3-yl)pyridine-2-carbonitrile
Canonical SMILESC#Cc1cc2c(cc1OC)-c1[nH]nc(-c3ccc(C#N)nc3)c1C2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.43
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
O14757 CHEK1 Homo sapiens Human PF00069 7.4 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.6 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.3 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.1 Ki ChEMBL