Molecule Details
| InChIKey | WONBUILDJNKYCB-AWEZNQCLSA-N |
|---|---|
| Compound Name | 6-(5-(((S)-azetidin-2-yl)methoxy)pyridine-3-yl)hex-5-yn-1-ol |
| Canonical SMILES | OCCCCC#Cc1cncc(OC[C@@H]2CCN2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.24 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 9.4 | Ki | ChEMBL |
| Q15822 | CHRNA2 | Homo sapiens | Human | PF02931 PF02932 | 8.4 | Ki | ChEMBL |
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 8.3 | IC50 | ChEMBL |
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | IC50 | ChEMBL;BindingDB |
| P30926 | CHRNB4 | Homo sapiens | Human | PF02931 PF02932 | 7.0 | Ki | ChEMBL |