InChIKey	WOFMFGQZHJDGCX-ZULDAHANSA-N
Compound Name	Mometasone Furoate
Canonical SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)CCl
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.44
Source	ChEMBL;BindingDB

DrugBank ID	DB14512
Drug Name	Mometasone furoate
CAS Number	83919-23-7
Groups	approved investigational vet_approved
ATC Codes	D07AC13 R03BA07 D07XC03 R01AD09 R03AK09
Description	Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906...

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Categories: Adrenal Cortex Hormones Adrenals Adrenergics, Inhalants Anti-Allergic Agents Anti-Inflammatory Agents Corticosteroids Corticosteroids, Dermatological Preparations Corticosteroids, Potent (Group III) Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) Cytochrome P-450 CYP2C8 Inhibitors (strong) Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Inducers Cytochrome P-450 CYP3A5 Inducers (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dermatologicals Drugs for Obstructive Airway Diseases Fused-Ring Compounds Glucocorticoids Hyperglycemia-Associated Agents Immunosuppressive Agents Nasal Preparations Pregnadienes Steroids Thyroxine-binding globulin inhibitors

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Cross-references: BindingDB: 50148733 ChEBI: 47564 CHEMBL1161 ChemSpider: 390091 Drugs Product Database (DPD): 7504 C07817 D00690 PDB: MOF RxCUI: 30145 Wikipedia: Mometasone ZINC: ZINC000003938677