Molecule Details
| InChIKey | WNSMPEBHTSITSG-LLVKDONJSA-N |
|---|---|
| Compound Name | 1-cyclopropyl-3-[(3R)-1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]urea |
| Canonical SMILES | CC(C)c1cc(C(=O)N2CC[C@@H](NC(=O)NC3CC3)C2)n[nH]1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.97 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UGL1 | KDM5B | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 7.4 | IC50 | ChEMBL;BindingDB |
| P29375 | KDM5A | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 7.1 | IC50 | ChEMBL;BindingDB |
| P41229 | KDM5C | Homo sapiens | Human | PF01388 PF02373 PF02375 PF21323 PF00628 PF08429 PF02928 | 6.5 | IC50 | ChEMBL;BindingDB |