Molecule Details
| InChIKey | WLXBZZLKNLKRKJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-Phenyl-6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidine |
| Canonical SMILES | c1ccc(-c2cnn3cc(-c4ccc(N5CCNCC5)cc4)cnc23)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.77 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 7.4 | IC50 | ChEMBL;BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 6.7 | IC50 | ChEMBL;BindingDB |
| P36897 | TGFBR1 | Homo sapiens | Human | PF01064 PF00069 PF08515 | 6.2 | IC50 | ChEMBL;BindingDB |