N-(3-ethynylphenyl)-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine

InChIKey	`WLLKPDBSPXZCTG-UHFFFAOYSA-N`
Compound Name	N-(3-ethynylphenyl)-6-{4-[(2-methanesulfonylethyl)amino]butoxy}quinazolin-4-amine
Canonical SMILES	`C#Cc1cccc(Nc2ncnc3ccc(OCCCCNCCS(C)(=O)=O)cc23)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.96
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.0	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.0	pIC50	TTD_MultiTarget