Molecule Details
InChIKeyWLKJMISWXHORCR-JTQLQIEISA-N
Compound Name6-(5-methyl-1H-pyrazol-4-yl)-2-[(2S)-piperidin-2-yl]thieno[3,2-d]pyrimidin-4(3H)-one
Canonical SMILESCc1n[nH]cc1-c1cc2nc([C@@H]3CCCCN3)[nH]c(=O)c2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.17
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UBU7 DBF4 Homo sapiens Human PF07535 9.4 IC50 ChEMBL;BindingDB
O00311 CDC7 Homo sapiens Human PF00069 8.7 IC50 ChEMBL;BindingDB
Q13627 DYRK1A Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
Q09013 DMPK Homo sapiens Human PF08826 PF00069 7.2 IC50 ChEMBL;BindingDB
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
P53355 DAPK1 Homo sapiens Human PF00023 PF12796 PF13637 PF00531 PF00069 6.7 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB
P24863 CCNC Homo sapiens Human PF16899 PF00134 6.5 IC50 ChEMBL;BindingDB
P49336 CDK8 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.4 IC50 ChEMBL;BindingDB