Molecule Details
InChIKeyWKEYMNLZBZKLOG-UHFFFAOYSA-N
Compound Name4-[4-(1H-benzimidazol-2-ylamino)phenyl]-2,3-dihydroisoindol-1-one
Canonical SMILESO=C1NCc2c1cccc2-c1ccc(Nc2nc3ccccc3[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.57
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 7.5 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 7.4 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.4 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.8 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.7 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.6 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.5 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.1 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.0 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.0 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL