Molecule Details
| InChIKey | WJEGHVYQRQOJAQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(3,5-dichloro-4-pyridinyl)-1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-3-methylindole-6-carboxamide |
| Canonical SMILES | Cc1noc(C)c1Cn1cc(C)c2ccc(C(=O)Nc3c(Cl)cncc3Cl)cc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.93 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 6.9 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 6.9 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 6.9 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 6.9 | IC50 | ChEMBL |