Molecule Details
| InChIKey | WJASKODGMHBDFO-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[4-[(6-Chloro-[1,3]dioxolo[4,5-B]pyridin-7-Yl)amino]-2-Pyridyl]cyclopropanecarboxamide |
| Canonical SMILES | O=C(Nc1cc(Nc2c(Cl)cnc3c2OCO3)ccn1)C1CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.43 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 8.9 | IC50 | ChEMBL |
| P36897 | TGFBR1 | Homo sapiens | Human | PF01064 PF00069 PF08515 | 8.7 | IC50 | ChEMBL |
| P36894 | BMPR1A | Homo sapiens | Human | PF01064 PF07714 PF08515 | 8.6 | IC50 | ChEMBL |
| P37023 | ACVRL1 | Homo sapiens | Human | PF07714 PF08515 | 8.4 | IC50 | ChEMBL |
| P36896 | ACVR1B | Homo sapiens | Human | PF01064 PF00069 PF08515 | 7.5 | IC50 | ChEMBL |