Molecule Details
| InChIKey | WIYUZYBFCWCCQJ-IFKAHUTRSA-N |
|---|---|
| Compound Name | Naltrindole |
| Canonical SMILES | Oc1ccc2c3c1O[C@H]1c4[nH]c5ccccc5c4C[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.05 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P41146 | OPRL1 | Homo sapiens | Human | PF00001 | 10.5 | Ki | ChEMBL |
| P41143 | OPRD1 | Homo sapiens | Human | PF00001 | 9.7 | Ki | ChEMBL;BindingDB |
| P41145 | OPRK1 | Homo sapiens | Human | PF00001 | 8.0 | Ki | ChEMBL;BindingDB |
| P35372 | OPRM1 | Homo sapiens | Human | PF00001 | 8.0 | Ki | ChEMBL;BindingDB |