Molecule Details
InChIKeyWIUDGBCTJVXBCM-KRWDZBQOSA-N
Compound Name(3S)-N-hydroxy-2,2-dimethyl-4-(4-phenoxyphenyl)sulfonylthiomorpholine-3-carboxamide
Canonical SMILESCC1(C)SCCN(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)[C@H]1C(=O)NO
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Homologous
Avg pChEMBL9.25
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P45452 MMP13 Homo sapiens Human PF00045 PF00413 PF01471 10.5 IC50 ChEMBL;BindingDB
P08253 MMP2 Homo sapiens Human PF00040 PF00045 PF00413 10.3 IC50 ChEMBL;BindingDB
P14780 MMP9 Homo sapiens Human PF00040 PF00045 PF00413 9.6 IC50 ChEMBL;BindingDB
P08254 MMP3 Homo sapiens Human PF00045 PF00413 PF01471 9.5 IC50 ChEMBL;BindingDB
P50281 MMP14 Homo sapiens Human PF11857 PF00045 PF00413 PF01471 9.5 IC50 ChEMBL;BindingDB
P03956 MMP1 Homo sapiens Human PF00045 PF00413 PF01471 8.1 IC50 ChEMBL;BindingDB
P09237 MMP7 Homo sapiens Human PF00413 PF01471 7.3 IC50 ChEMBL;BindingDB