InChIKey	WIIZWVCIJKGZOK-RKDXNWHRSA-N
Compound Name	Chloramphenicol
Canonical SMILES	O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	6.37
Source	ChEMBL

DrugBank ID	DB00446
Drug Name	Chloramphenicol
CAS Number	56-75-7
Groups	approved vet_approved withdrawn
ATC Codes	D06AX02 S02AA01 D10AF03 S01AA01 G01AA05 J01BA01 S03AA08
Description	An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (Fr...

---

Categories: Alcohols Amphenicols Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antibiotics for Topical Use Antiinfectives for Systemic Use Antiinfectives for Treatment of Acne Benzene Derivatives Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (strong) Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 CYP3A5 Inhibitors Cytochrome P-450 CYP3A5 Inhibitors (strength unknown) Cytochrome P-450 CYP3A7 Inhibitors Cytochrome P-450 CYP3A7 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Dermatologicals Enzyme Inhibitors Genito Urinary System and Sex Hormones Glycols Gynecological Antiinfectives and Antiseptics Immunosuppressive Agents Myelosuppressive Agents Nitro Compounds Nitrobenzenes OAT1/SLC22A6 inhibitors Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Propylene Glycols Protein Synthesis Inhibitors Sensory Organs

---

Cross-references: BindingDB: 23447 ChEBI: 17698 CHEMBL130 ChemSpider: 5744 Drugs Product Database (DPD): 16112 C00918 D00104 PDB: CLM PharmGKB: PA448927 PubChem:5959 PubChem:46505318 RxCUI: 2348 Therapeutic Targets Database: DAP001356 Wikipedia: Chloramphenicol ZINC: ZINC000000113382